8cv7: Difference between revisions

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-'''Unreleased structure'''
-The entry 8cv7 is ON HOLD
+==Peptide 2.2E in complex with BRD2-BD2==
+<StructureSection load='8cv7' size='340' side='right'caption='[[8cv7]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-Authors: Franck, C., Mackay, J.P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8cv7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CV7 FirstGlance]. <br>
-Description: Peptide 2.2E in complex with BRD2-BD2
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-[[Category: Mackay, J.P]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cv7 OCA], [https://pdbe.org/8cv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cv7 RCSB], [https://www.ebi.ac.uk/pdbsum/8cv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cv7 ProSAT]</span></td></tr>
-[[Category: Franck, C]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Franck C]]
+[[Category: Mackay JP]]