7q32: Difference between revisions

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<StructureSection load='7q32' size='340' side='right'caption='[[7q32]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='7q32' size='340' side='right'caption='[[7q32]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7q32]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q32 FirstGlance]. <br>
<table><tr><td colspan='2'>[[7q32]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q32 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q32 OCA], [https://pdbe.org/7q32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q32 RCSB], [https://www.ebi.ac.uk/pdbsum/7q32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q32 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q32 OCA], [https://pdbe.org/7q32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q32 RCSB], [https://www.ebi.ac.uk/pdbsum/7q32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q32 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UDP_ECOLI UDP_ECOLI]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.  
[https://www.uniprot.org/uniprot/UDP_ECOLI UDP_ECOLI] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
 
==See Also==
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Uridine phosphorylase]]
[[Category: Antipov A]]
[[Category: Antipov, A]]
[[Category: Mordkovich N]]
[[Category: Mordkovich, N]]
[[Category: Okorokova N]]
[[Category: Okorokova, N]]
[[Category: Polyakov K]]
[[Category: Polyakov, K]]
[[Category: Safonova T]]
[[Category: Safonova, T]]
[[Category: Veiko V]]
[[Category: Veiko, V]]
[[Category: Mutant enzyme]]
[[Category: Transferase]]

Latest revision as of 16:13, 1 February 2024

Mutant D24G of uridine phosphorylase from E. coliMutant D24G of uridine phosphorylase from E. coli

Structural highlights

7q32 is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UDP_ECOLI Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

See Also

7q32, resolution 1.70Å

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