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==Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain== | |||
<StructureSection load='7uw3' size='340' side='right'caption='[[7uw3]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7uw3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus Severe acute respiratory syndrome coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UW3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uw3 OCA], [https://pdbe.org/7uw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uw3 RCSB], [https://www.ebi.ac.uk/pdbsum/7uw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uw3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | |||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Severe acute respiratory syndrome coronavirus]] | |||
[[Category: Calero G]] |
Latest revision as of 12:57, 25 October 2023
Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal DomainStructure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain
Structural highlights
FunctionNCAP_SARS2 Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. See Also |
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