2uxh: Difference between revisions
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<StructureSection load='2uxh' size='340' side='right'caption='[[2uxh]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2uxh' size='340' side='right'caption='[[2uxh]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2uxh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2uxh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxh OCA], [https://pdbe.org/2uxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxh RCSB], [https://www.ebi.ac.uk/pdbsum/2uxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxh OCA], [https://pdbe.org/2uxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxh RCSB], [https://www.ebi.ac.uk/pdbsum/2uxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TTGR_PSEPT TTGR_PSEPT] Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.<ref>PMID:11251828</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alguel | [[Category: Pseudomonas putida]] | ||
[[Category: Gallegos | [[Category: Alguel Y]] | ||
[[Category: Krell | [[Category: Gallegos M-T]] | ||
[[Category: Meng | [[Category: Krell T]] | ||
[[Category: Ramos | [[Category: Meng C]] | ||
[[Category: Teran | [[Category: Ramos JL]] | ||
[[Category: Zhang | [[Category: Teran W]] | ||
[[Category: Zhang X]] | |||