3ed1: Difference between revisions

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<StructureSection load='3ed1' size='340' side='right'caption='[[3ed1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3ed1' size='340' side='right'caption='[[3ed1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ed1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ED1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ED1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ed1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ED1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ED1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA3:GIBBERELLIN+A3'>GA3</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ebl|3ebl]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA3:GIBBERELLIN+A3'>GA3</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GID1, Os05g0407500, LOC_Os05g33730, OJ1657_H11.10, P0040B10.6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ed1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ed1 OCA], [https://pdbe.org/3ed1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ed1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ed1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ed1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ed1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ed1 OCA], [https://pdbe.org/3ed1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ed1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ed1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ed1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GID1_ORYSJ GID1_ORYSJ]] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.  
[https://www.uniprot.org/uniprot/GID1_ORYSJ GID1_ORYSJ] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Japanese rice]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kato, H]]
[[Category: Oryza sativa Japonica Group]]
[[Category: Matsuoka, M]]
[[Category: Kato H]]
[[Category: Nakatsu, T]]
[[Category: Matsuoka M]]
[[Category: Shimada, A]]
[[Category: Nakatsu T]]
[[Category: Ueguchi-Tanaka, M]]
[[Category: Shimada A]]
[[Category: Alpha/beta hydrolase]]
[[Category: Ueguchi-Tanaka M]]
[[Category: Gibberellin signaling pathway]]
[[Category: Hydrolase]]
[[Category: Hydrolase receptor]]
[[Category: Lipase]]
[[Category: Nucleus]]
[[Category: Receptor]]

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