7trp: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 7trp is ON HOLD
+==Human M4 muscarinic acetylcholine receptor complex with Gi1 and the agonist iperoxo and positive allosteric modulator LY2033298==
+<StructureSection load='7trp' size='340' side='right'caption='[[7trp]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7trp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TRP FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUE:3-azanyl-5-chloranyl-~{N}-cyclopropyl-6-methoxy-4-methyl-thieno[2,3-b]pyridine-2-carboxamide'>IUE</scene>, <scene name='pdbligand=IXO:4-(4,5-DIHYDRO-1,2-OXAZOL-3-YLOXY)-N,N,N-TRIMETHYLBUT-2-YN-1-AMINIUM'>IXO</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7trp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7trp OCA], [https://pdbe.org/7trp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7trp RCSB], [https://www.ebi.ac.uk/pdbsum/7trp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7trp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
-Authors:
+==See Also==
+*[[Muscarinic acetylcholine receptor|Muscarinic acetylcholine receptor]]
-Description:
+*[[Transducin 3D structures|Transducin 3D structures]]
-[[Category: Unreleased Structures]]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Belousoff MJ]]
+[[Category: Danev R]]
+[[Category: Glukhova A]]
+[[Category: Mobbs JI]]
+[[Category: Sexton PM]]
+[[Category: Thal DM]]
+[[Category: Vuckovic Z]]