3da2: Difference between revisions

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<StructureSection load='3da2' size='340' side='right'caption='[[3da2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='3da2' size='340' side='right'caption='[[3da2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DA2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DA2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA13 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3da2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3da2 OCA], [https://pdbe.org/3da2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3da2 RCSB], [https://www.ebi.ac.uk/pdbsum/3da2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3da2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3da2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3da2 OCA], [https://pdbe.org/3da2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3da2 RCSB], [https://www.ebi.ac.uk/pdbsum/3da2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3da2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN]] Reversible hydration of carbon dioxide.  
[https://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN] Reversible hydration of carbon dioxide.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Bray, J E]]
[[Category: Bray JE]]
[[Category: Delft, F von]]
[[Category: Edwards AM]]
[[Category: Edwards, A M]]
[[Category: Filippakopoulos P]]
[[Category: Filippakopoulos, P]]
[[Category: King ONF]]
[[Category: King, O N.F]]
[[Category: Oppermann U]]
[[Category: Oppermann, U]]
[[Category: Picaud SS]]
[[Category: Picaud, S S]]
[[Category: Pike ACW]]
[[Category: Pike, A C.W]]
[[Category: Pilka ES]]
[[Category: Pilka, E S]]
[[Category: Roos AK]]
[[Category: Roos, A K]]
[[Category: Wikstrom M]]
[[Category: Structural genomic]]
[[Category: Yue WW]]
[[Category: Wikstrom, M]]
[[Category: Von Delft F]]
[[Category: Yue, W W]]
[[Category: Carbonic anhydrase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Sgc]]
[[Category: Sulfonamide]]

Latest revision as of 15:43, 30 August 2023

X-ray structure of human carbonic anhydrase 13 in complex with inhibitorX-ray structure of human carbonic anhydrase 13 in complex with inhibitor

Structural highlights

3da2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAH13_HUMAN Reversible hydration of carbon dioxide.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3da2, resolution 2.05Å

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OCA
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