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| The <scene name='38/382958/Cv/4'>active site of PEP contains the serine protease catalytic triad of Ser-His-Asp</scene><ref>PMID:19006380</ref>. Triad is colored in salmon. | | The <scene name='38/382958/Cv/4'>active site of PEP contains the serine protease catalytic triad of Ser-His-Asp</scene><ref>PMID:19006380</ref>. Triad is colored in salmon. |
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| </StructureSection>
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| ==3D structures of prolyl endopeptidase== | | ==3D structures of prolyl endopeptidase== |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | [[Prolyl endopeptidase 3D structures]] |
| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *Prolyl endopeptidase open state
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| **[[3iun]], [[3ium]], [[3iul]], [[3iuj]] – ApPEP - ''Aeromonas punctata''<br />
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| **[[3iur]] – ApPEP + villin headpiece peptide
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| *Prolyl endopeptidase closed state
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| **[[3iuq]], [[3ivm]] - ApPEP + z-pro-prolinal<br />
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| **[[3muo]] – ApPEP (mutant) + z-pro-prolinal<br />
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| **[[3mun]] - ApPEP (mutant)
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| *Prolyl endopeptidase
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| **[[7obm]] – hPEP 90-727 - human <br />
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| **[[1h2w]], [[1qfm]] – pPEP - pig<br />
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| **[[1vz2]], [[1vz3]], [[1h2x]], [[1e5t]], [[4ax4]] – pPEP (mutant) <br />
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| **[[6jci]], [[6jym]] – PEP - abalone <br />
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| **[[1yr2]] – PEP – ''Novosphingobium capsulatum''<br />
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| **[[6can]] – PfPEP (mutant) - ''Pyrococcus furiosus''<br />
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| **[[6jym]] – HdhPEP – ''Haliotis discus hannai''<br />
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| *Prolyl endopeptidase complex with inhibitor
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| **[[3ddu]] – hPEP + pyridone derivative inhibitor<br />
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| **[[6y0f]] – hPEP + drug <br />
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| **[[2xdw]] – pPEP + peptide<br />
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| **[[1uoo]], [[1uop]], [[1uoq]], [[1o6f]], [[1o6g]], [[1h2z]], [[1e8n]] - pPEP (mutant) + peptide<br />
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| **[[1h2y]] - pPEP (mutant) + z-pro-prolinal<br />
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| **[[1qfs]] - pPEP + z-pro-prolinal<br />
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| **[[3eq7]], [[3eq8]], [[3eq9]] – pPEP + benzyloxy-carbonyl-gly-pro inhibitor<br />
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| **[[1e8m]] - pPEP + pro-(decarboxy-pro) inhibitor<br />
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| **[[4amy]], [[4amz]], [[4an0]], [[4an1]], [[4bcb]], [[4bcc]], [[4bcd]] - pPEP + pyrrolidine derivative inhibitor<br />
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| **[[6jci]] - HdhPEP + pyrrolidine derivative inhibitor<br />
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| **[[2bkl]] - PEP + z-ala-prolinal – ''Myxococcus xanthus''<br />
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| **[[5t88]] - PfPEP + Pro <br />
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| }}
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| ==References== | | ==References== |
| <References/> | | <References/> |
| | </StructureSection> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |