Human growth hormone: Difference between revisions
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Mature hGH travels through the bloodstream and interacts with a specific hGH-receptor on the surface of various cells, including muscle, bone, and cartilage. Binding of hGH to its receptor causes dimerization and signal transduction, which ultimately stimulates cellular division. HGH also indirectly influences growth by stimulating the liver to produce additional growth factors, such as insulin-like growth factor-1. Synthetic versions of hGH produced by recombinant DNA technology are used to treat growth disorders associated with hGH deficiencies. [[Prolactin receptor]] (PRLR) can also bind to and be activated by growth hormone. | Mature hGH travels through the bloodstream and interacts with a specific hGH-receptor on the surface of various cells, including muscle, bone, and cartilage. Binding of hGH to its receptor causes dimerization and signal transduction, which ultimately stimulates cellular division. HGH also indirectly influences growth by stimulating the liver to produce additional growth factors, such as insulin-like growth factor-1. Synthetic versions of hGH produced by recombinant DNA technology are used to treat growth disorders associated with hGH deficiencies. [[Prolactin receptor]] (PRLR) can also bind to and be activated by growth hormone. | ||
See also [[HUMAN GROWTH HORMONE (HEBREW)]] | |||
==Location in the Body== | ==Location in the Body== | ||
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== References == | == References == | ||
<references/> | <references/> | ||
*12. ANDERSON, Lloyd (2012). Nanobiology and physiology of growth hormone secretion. Experimental Biology and Medicine. Experimental biology and medicine. https://doi.org/10.1258/ebm.2011.011306 | |||
*13. Clarence J. Gibbs, Jr., Ph.D., Anthony Joy, D.O., Reid Heffner, M.D., Maryellen Franko, Ph.D., Masayuki Miyazaki, M.D., David M. Asher, M.D., Joseph E. Parisi, M.D., Paul W. Brown, M.D., and D. Carleton Gajdusek, M.D. (1985). Clinical and Pathological Features and Laboratory Confirmation of Creutzfeldt–Jakob Disease in a Recipient of Pituitary-Derived Human Growth Hormone. The New England Journal of Medicine. https://www.nejm.org/doi/pdf/10.1056/NEJM198509193131207 | |||
*14. Orthopedic Institute for Children. Turner Syndrome. Consulted on January 2022. URL : https://www.ortho-institute.org/patient-care/orthopedic-specialties/skeletal-dysplasia-dwarfism/turner-syndrome/ | |||
==See Also== | ==See Also== | ||
* [[Hormone]] | * [[Hormone]] | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||