2xql: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xql]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQL FirstGlance]. <br> | <table><tr><td colspan='2'>[[2xql]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQL FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 19.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xql OCA], [https://pdbe.org/2xql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xql RCSB], [https://www.ebi.ac.uk/pdbsum/2xql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xql ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xql OCA], [https://pdbe.org/2xql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xql RCSB], [https://www.ebi.ac.uk/pdbsum/2xql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xql ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aloria | [[Category: Aloria K]] | ||
[[Category: Arizmendi | [[Category: Arizmendi JM]] | ||
[[Category: Ausio | [[Category: Ausio J]] | ||
[[Category: Bretana | [[Category: Bretana L]] | ||
[[Category: Finn | [[Category: Finn R]] | ||
[[Category: Martin-Benito | [[Category: Martin-Benito J]] | ||
[[Category: Muga | [[Category: Muga A]] | ||
[[Category: Prado | [[Category: Prado A]] | ||
[[Category: Ramos | [[Category: Ramos I]] | ||
[[Category: Valpuesta | [[Category: Valpuesta JM]] | ||