2e8t: Difference between revisions
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<StructureSection load='2e8t' size='340' side='right'caption='[[2e8t]], [[Resolution|resolution]] 2.13Å' scene=''> | <StructureSection load='2e8t' size='340' side='right'caption='[[2e8t]], [[Resolution|resolution]] 2.13Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2e8t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2e8t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E8T FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e8t OCA], [https://pdbe.org/2e8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e8t RCSB], [https://www.ebi.ac.uk/pdbsum/2e8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e8t ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e8t OCA], [https://pdbe.org/2e8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e8t RCSB], [https://www.ebi.ac.uk/pdbsum/2e8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e8t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/GGPPS_YEAST GGPPS_YEAST] Catalyzes the trans-addition of the 3 molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate. Required for the membrane attachment of YPT1 and SEC4. May be involved in vesicle trafficking and protein sorting.<ref>PMID:7665600</ref> <ref>PMID:15296494</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chang | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Chen | [[Category: Chang TH]] | ||
[[Category: Guo | [[Category: Chen CK-M]] | ||
[[Category: Jeng | [[Category: Guo RT]] | ||
[[Category: Ko | [[Category: Jeng WY]] | ||
[[Category: Liang | [[Category: Ko TP]] | ||
[[Category: Oldfield | [[Category: Liang PH]] | ||
[[Category: Wang | [[Category: Oldfield E]] | ||
[[Category: Wang AH-J]] | |||