2d6m: Difference between revisions

No edit summary
No edit summary
 
Line 3: Line 3:
<StructureSection load='2d6m' size='340' side='right'caption='[[2d6m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2d6m' size='340' side='right'caption='[[2d6m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d6m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D6M FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d6m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D6M FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2d6k|2d6k]], [[2d6l|2d6l]], [[2d6n|2d6n]], [[2d6o|2d6o]], [[2d6p|2d6p]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d6m OCA], [https://pdbe.org/2d6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d6m RCSB], [https://www.ebi.ac.uk/pdbsum/2d6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d6m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d6m OCA], [https://pdbe.org/2d6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d6m RCSB], [https://www.ebi.ac.uk/pdbsum/2d6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d6m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG9_MOUSE LEG9_MOUSE] Binds galactosides. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 37:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Kato, R]]
[[Category: Kato R]]
[[Category: Nagae, M]]
[[Category: Nagae M]]
[[Category: Nakamura, T]]
[[Category: Nakamura T]]
[[Category: Nishi, N]]
[[Category: Nishi N]]
[[Category: Wakatsuki, S]]
[[Category: Wakatsuki S]]
[[Category: Beta sandwich]]
[[Category: Carbohydrate binding protein]]
[[Category: Galectin]]
[[Category: Structural genomic]]
[[Category: Sugar binding protein]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA