2bcu: Difference between revisions
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<StructureSection load='2bcu' size='340' side='right'caption='[[2bcu]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2bcu' size='340' side='right'caption='[[2bcu]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bcu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2bcu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcu OCA], [https://pdbe.org/2bcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcu RCSB], [https://www.ebi.ac.uk/pdbsum/2bcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcu OCA], [https://pdbe.org/2bcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcu RCSB], [https://www.ebi.ac.uk/pdbsum/2bcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 2bcu" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2bcu" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bebenek | [[Category: Bebenek K]] | ||
[[Category: Garcia-Diaz | [[Category: Garcia-Diaz M]] | ||
[[Category: Krahn | [[Category: Krahn JM]] | ||
[[Category: Kunkel | [[Category: Kunkel TA]] | ||
[[Category: Pedersen | [[Category: Pedersen LC]] | ||