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==Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor== | |||
<StructureSection load='7m3h' size='340' side='right'caption='[[7m3h]], [[Resolution|resolution]] 1.27Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7m3h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M3H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YPV:5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic+acid'>YPV</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m3h OCA], [https://pdbe.org/7m3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m3h RCSB], [https://www.ebi.ac.uk/pdbsum/7m3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m3h ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A4U3MLJ4_ENTFL A0A4U3MLJ4_ENTFL] | |||
==See Also== | |||
*[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Enterococcus faecalis]] | ||
[[Category: Bose | [[Category: Large Structures]] | ||
[[Category: Steussy | [[Category: Bose S]] | ||
[[Category: Stauffacher CV]] | |||
[[Category: Steussy CN]] | |||
Latest revision as of 19:04, 18 October 2023
Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitorTargeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
Structural highlights
FunctionSee Also |
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