21bi: Difference between revisions

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<StructureSection load='21bi' size='340' side='right'caption='[[21bi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='21bi' size='340' side='right'caption='[[21bi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[21bi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=21BI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=21BI FirstGlance]. <br>
<table><tr><td colspan='2'>[[21bi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=21BI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=21BI FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=21bi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=21bi OCA], [https://pdbe.org/21bi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=21bi RCSB], [https://www.ebi.ac.uk/pdbsum/21bi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=21bi ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=21bi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=21bi OCA], [https://pdbe.org/21bi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=21bi RCSB], [https://www.ebi.ac.uk/pdbsum/21bi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=21bi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref>
[https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gilliland, G L]]
[[Category: Gilliland GL]]
[[Category: Hirai, Y]]
[[Category: Hirai Y]]
[[Category: Masui, Y]]
[[Category: Masui Y]]
[[Category: Poulos, T L]]
[[Category: Poulos TL]]
[[Category: Veerapandian, B]]
[[Category: Veerapandian B]]
[[Category: Cytokine]]

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