Metabotropic glutamate receptor 3D structures: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 4: | Line 4: | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*Metabotropic glutamate receptor 1 | *Metabotropic glutamate receptor 1; Domains – LBD 1-564; transmembrane 569-836 | ||
**[[7dgd]] – hMGluR1 - human – Cryo EM<br /> | **[[7dgd]] – hMGluR1 - human – Cryo EM<br /> | ||
| Line 14: | Line 14: | ||
**[[1iss]] - rMGluR1 LBD + antagonist<br /> | **[[1iss]] - rMGluR1 LBD + antagonist<br /> | ||
*Metabotropic glutamate receptor 2 | *Metabotropic glutamate receptor 2 | ||
**[[7epa]] – hMGluR2 – Cryo EM<br /> | **[[7epa]] – hMGluR2 – Cryo EM<br /> | ||
| Line 27: | Line 27: | ||
**[[5cni]] – hMGluR2 LBD + Glu <br /> | **[[5cni]] – hMGluR2 LBD + Glu <br /> | ||
**[[5cnj]] – hMGluR2 LBD + Glu analog<br /> | **[[5cnj]] – hMGluR2 LBD + Glu analog<br /> | ||
**[[7epe]], [[7epf]] – hMGluR2 | **[[7epe]], [[7epf]] – hMGluR2 transmembrane domain + antagonist + FMN<br /> | ||
*Metabotropic glutamate receptor 3 | *Metabotropic glutamate receptor 3 | ||
**[[7wi6]], [[7wi8]], [[7wih]] – hMGluR3 – Cryo EM<br /> | |||
**[[5cnk]] – hMGluR3 LBD + Glu <br /> | **[[5cnk]] – hMGluR3 LBD + Glu <br /> | ||
**[[3sm9]] - hMGluR3 + antagonist<br /> | **[[3sm9]] - hMGluR3 + antagonist<br /> | ||
| Line 40: | Line 41: | ||
*Metabotropic glutamate receptor 4 | *Metabotropic glutamate receptor 4 | ||
**[[8jd6]] – hMGluR4 in Gi complex – Cryo EM<br /> | |||
**[[7e9h]] – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM<br /> | **[[7e9h]] – hMGluR4 in Gi complex + antagonist + scFv – Cryo EM<br /> | ||
| Line 50: | Line 52: | ||
**[[6ffh]], [[6ffi]] - hMGluR5 LBD (mutant) + positive allosteric modulator<br /> | **[[6ffh]], [[6ffi]] - hMGluR5 LBD (mutant) + positive allosteric modulator<br /> | ||
**[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu<br /> | **[[3lmk]] – hMGluR5 LBD (mutant) + positive allosteric modulator + Glu<br /> | ||
**[[5cgc]], [[5cgd]] - hMGluR5 transmembrane domain + negative allosteric modulator<br /> | **[[4oo9]], [[5cgc]], [[5cgd]] - hMGluR5 transmembrane domain + negative allosteric modulator<br /> | ||
**[[7p2l]] - hMGluR5 transmembrane domain (mutant) 569-836 + negative allosteric modulator<br /> | **[[7p2l]] - hMGluR5 transmembrane domain (mutant) 569-836 + negative allosteric modulator<br /> | ||
| Line 64: | Line 66: | ||
**[[6bt5]] – hMGluR8 LBD + phosphonobutanoic acid <br /> | **[[6bt5]] – hMGluR8 LBD + phosphonobutanoic acid <br /> | ||
**[[6e5v]] – hMGluR8 N-terminal (mutant) + inhibitor <br /> | **[[6e5v]] – hMGluR8 N-terminal (mutant) + inhibitor <br /> | ||
*Metabotropic glutamate receptor 2+3 | |||
**[[8jcu]], [[8jcv]], [[8jcw]], [[8jcx]], [[8jcy]], [[8jcz]], [[8jd0]], [[8jd1]], [[8jd2]] – hMGluR – Cryo EM<br /> | |||
**[[8jd3]] – hMGluR in GI complex – Cryo EM<br /> | |||
*Metabotropic glutamate receptor 2+4 | |||
**[[8jd4]] – hMGluR – Cryo EM<br /> | |||
**[[8jd5]] – hMGluR in GI complex – Cryo EM<br /> | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||