2bid: Difference between revisions
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==HUMAN PRO-APOPTOTIC PROTEIN BID== | ==HUMAN PRO-APOPTOTIC PROTEIN BID== | ||
<StructureSection load='2bid' size='340' side='right'caption='[[2bid | <StructureSection load='2bid' size='340' side='right'caption='[[2bid]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2bid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BID FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bid OCA], [https://pdbe.org/2bid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bid RCSB], [https://www.ebi.ac.uk/pdbsum/2bid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bid ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bid OCA], [https://pdbe.org/2bid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bid RCSB], [https://www.ebi.ac.uk/pdbsum/2bid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bid ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/BID_HUMAN BID_HUMAN] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.<ref>PMID:14583606</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chou | [[Category: Chou JJ]] | ||
[[Category: Li | [[Category: Li H]] | ||
[[Category: Salvesen | [[Category: Salvesen GS]] | ||
[[Category: Wagner | [[Category: Wagner G]] | ||
[[Category: Yuan | [[Category: Yuan J]] | ||