7kae: Difference between revisions
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==Rop protein variant with a buried tryptophan== | ==Rop protein variant with a buried tryptophan== | ||
<StructureSection load='7kae' size='340' side='right'caption='[[7kae]]' scene=''> | <StructureSection load='7kae' size='340' side='right'caption='[[7kae]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KAE FirstGlance]. <br> | <table><tr><td colspan='2'>[[7kae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KAE FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kae OCA], [https://pdbe.org/7kae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kae RCSB], [https://www.ebi.ac.uk/pdbsum/7kae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kae ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kae OCA], [https://pdbe.org/7kae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kae RCSB], [https://www.ebi.ac.uk/pdbsum/7kae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kae ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events. | |||
==See Also== | |||
*[[Rop protein|Rop protein]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Gallagher DT]] | [[Category: Gallagher DT]] | ||
[[Category: Hoopes JT]] | [[Category: Hoopes JT]] | ||
[[Category: Karageorgos I]] | [[Category: Karageorgos I]] | ||
Latest revision as of 18:20, 18 October 2023
Rop protein variant with a buried tryptophanRop protein variant with a buried tryptophan
Structural highlights
FunctionROP_ECOLX Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events. See Also |
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