Janus kinase 3D structures: Difference between revisions
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**[[4gfm]], [[4gmy]], [[4iva]], [[4ivb]], [[4ivc]], [[4ivd]], [[4ji9]], [[4jia]], [[5usy]], [[5usz]], [[5ut0]], [[5ut1]], [[5ut2]], [[5ut3]], [[5ut4]], [[5ut5]], [[5ut6]], [[6drw]], [[5wev]] - hJAK2 JH1 domain + PTyr + inhibitor <br /> | **[[4gfm]], [[4gmy]], [[4iva]], [[4ivb]], [[4ivc]], [[4ivd]], [[4ji9]], [[4jia]], [[5usy]], [[5usz]], [[5ut0]], [[5ut1]], [[5ut2]], [[5ut3]], [[5ut4]], [[5ut5]], [[5ut6]], [[6drw]], [[5wev]] - hJAK2 JH1 domain + PTyr + inhibitor <br /> | ||
**[[5hez]] - hJAK2 JH1 domain (mutant) + PTyr + inhibitor <br /> | **[[5hez]] - hJAK2 JH1 domain (mutant) + PTyr + inhibitor <br /> | ||
**[[6bbv]] - hJAK2 JH1 domain + inhibitor <br /> | **[[6bbv]], [[6wtp]], [[7ll4]], [[7ll5]], [[7q7i]], [[7q7k]], [[7q7l]], [[7q7w]], [[7rn6]], [[7uyw]] - hJAK2 JH1 domain + inhibitor <br /> | ||
*''JAK2 JH2 or pseudokinase domain residues 536-812'' | *''JAK2 JH2 or pseudokinase domain residues 536-812'' | ||
**[[6obb]] - hJAK2 JH2 domain + inhibitor <br /> | **[[7f7w]] – hJAK2 JH2 domain <br /> | ||
**[[6brw]], [[6d2i]], [[6bs0]], [[6bss]], [[5wij]], [[5wik]], [[5wil]], [[5wim]], [[5win]], [[6g3c]], [[6m9h]], [[6oav]], [[6obf]], [[6obl]], [[6occ]], [[6x8e]], [[6xjk]], [[7jyo]], [[7jyq]] - hJAK2 JH2 domain (mutant) + inhibitor <br /> | **[[6obb]], [[7t0p]] - hJAK2 JH2 domain + inhibitor <br /> | ||
**[[6brw]], [[6d2i]], [[6bs0]], [[6bss]], [[5wij]], [[5wik]], [[5wil]], [[5wim]], [[5win]], [[6g3c]], [[6m9h]], [[6oav]], [[6obf]], [[6obl]], [[6occ]], [[6x8e]], [[6xjk]], [[7jyo]], [[7jyq]], [[7t1t]], [[8b8n]], [[8b8u]], [[8b99]], [[8b9e]], [[8b9h]], [[8ba2]], [[8bab]], [[8bak]], [[8ex0]], [[8ex1]], [[8ex2]] - hJAK2 JH2 domain (mutant) + inhibitor <br /> | |||
**[[8ba3]], [[8ba4]] - hJAK2 JH2 domain (mutant) + drug<br /> | |||
**[[3ugc]] – hJAK2 JH2 domain (mutant) <br /> | **[[3ugc]] – hJAK2 JH2 domain (mutant) <br /> | ||
**[[4fvq]], [[4fvr]], [[5i4n]] – hJAK2 JH2 domain (mutant) + ATP<br /> | **[[4fvq]], [[4fvr]], [[5i4n]] – hJAK2 JH2 domain (mutant) + ATP<br /> | ||
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**[[1yvj]] – hJAK3 kinase domain (mutant) + PTyr + staurosporine analog<br /> | **[[1yvj]] – hJAK3 kinase domain (mutant) + PTyr + staurosporine analog<br /> | ||
**[[3lxk]], [[3lxl]], [[5wfj]] – hJAK3 kinase domain (mutant) + PTyr + inhibitor <br /> | **[[3lxk]], [[3lxl]], [[5wfj]] – hJAK3 kinase domain (mutant) + PTyr + inhibitor <br /> | ||
**[[3pjc]], [[4v0g]], [[4z16]], [[5lwm]], [[5lwn]], [[5toz]], [[6glb]], [[6gl9]], [[6gla]], [[6ny4]], [[6dud]], [[6da4]], [[7apf]], [[7apg]] – hJAK3 kinase domain + inhibitor <br /> | **[[3pjc]], [[4v0g]], [[4z16]], [[5lwm]], [[5lwn]], [[5toz]], [[6glb]], [[6gl9]], [[6gla]], [[6ny4]], [[6dud]], [[6da4]], [[7apf]], [[7apg]], [[7q6h]], [[7uyv]] – hJAK3 kinase domain + inhibitor <br /> | ||
**[[4hvd]], [[4hvg]], [[4hvh]], [[4hvi]], [[3zc6]], [[3zep]], [[4i6q]], [[4qps]], [[4rio]], [[4qt1]], [[5tts]], [[5ttu]], [[5ttv]], [[5vo6]], [[6db3]], [[6db4]] – hJAK3 kinase domain (mutant) + inhibitor <br /> | **[[4hvd]], [[4hvg]], [[4hvh]], [[4hvi]], [[3zc6]], [[3zep]], [[4i6q]], [[4qps]], [[4rio]], [[4qt1]], [[5tts]], [[5ttu]], [[5ttv]], [[5vo6]], [[6db3]], [[6db4]] – hJAK3 kinase domain (mutant) + inhibitor <br /> | ||
**[[5w86]], [[6hzv]] – hJAK3 kinase domain + PTyr + inhibitor <br /> | **[[5w86]], [[6hzv]] – hJAK3 kinase domain + PTyr + inhibitor <br /> | ||
**[[7c3n]] – hJAK3 kinase domain + PTyr + drug <br /> | **[[7c3n]] – hJAK3 kinase domain + PTyr + drug <br /> | ||
**[[6aak]] – hJAK3 kinase domain (mutant) + PTyr + drug <br /> | **[[6aak]] – hJAK3 kinase domain (mutant) + PTyr + drug <br /> | ||
*JAK | |||
**[[7t6f]], [[8ewy]] – mJAK + interferon lambda receptor 1 <br /> | |||
*TYK2 see [[Tyrosine kinase]] | *TYK2 see [[Tyrosine kinase]] | ||