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New page: ==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120== <StructureSection load='5sc7' size='340' side='right'caption='5sc7' scene=''... |
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==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120== | ==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120== | ||
<StructureSection load='5sc7' size='340' side='right'caption='[[5sc7]]' scene=''> | <StructureSection load='5sc7' size='340' side='right'caption='[[5sc7]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SC7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5sc7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SC7 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sc7 OCA], [https://pdbe.org/5sc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sc7 RCSB], [https://www.ebi.ac.uk/pdbsum/5sc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sc7 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.197Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=W2M:(2R)-1,4-dihydro-2H-spiro[pyrrolidine-2,3-quinolin]-2-one'>W2M</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sc7 OCA], [https://pdbe.org/5sc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sc7 RCSB], [https://www.ebi.ac.uk/pdbsum/5sc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sc7 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | |||
[[Category: Bezerra GA]] | [[Category: Bezerra GA]] | ||
[[Category: Bountra C]] | [[Category: Bountra C]] | ||
Latest revision as of 18:30, 6 March 2024
CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120
Structural highlights
FunctionCD44_MOUSE Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. |
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