1pen: Difference between revisions
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<StructureSection load='1pen' size='340' side='right'caption='[[1pen]], [[Resolution|resolution]] 1.10Å' scene=''> | <StructureSection load='1pen' size='340' side='right'caption='[[1pen]], [[Resolution|resolution]] 1.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1pen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1pen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_pennaceus Conus pennaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PEN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pen OCA], [https://pdbe.org/1pen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pen RCSB], [https://www.ebi.ac.uk/pdbsum/1pen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pen ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pen OCA], [https://pdbe.org/1pen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pen RCSB], [https://www.ebi.ac.uk/pdbsum/1pen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pen ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CA1A_CONPE CA1A_CONPE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian nAChRs (alpha-3/beta-2 > alpha-7 > alpha-3/beta-4).<ref>PMID:10545176</ref> <ref>PMID:8068627</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Conus pennaceus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alewood | [[Category: Alewood PF]] | ||
[[Category: Craik | [[Category: Craik DJ]] | ||
[[Category: Gehrmann | [[Category: Gehrmann J]] | ||
[[Category: Guddat | [[Category: Guddat LW]] | ||
[[Category: Hu | [[Category: Hu S-H]] | ||
[[Category: Martin | [[Category: Martin JL]] | ||