1hq3: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hq3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQ3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1hq3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQ3 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq3 OCA], [https://pdbe.org/1hq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hq3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq3 OCA], [https://pdbe.org/1hq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hq3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baldwin | [[Category: Baldwin JP]] | ||
[[Category: Chantalat | [[Category: Chantalat L]] | ||
[[Category: Donovan | [[Category: Donovan MJ]] | ||
[[Category: Lambert | [[Category: Lambert SJ]] | ||
[[Category: Nicholson | [[Category: Nicholson JM]] | ||
[[Category: Reid | [[Category: Reid AJ]] | ||
[[Category: Reynolds | [[Category: Reynolds CD]] | ||
[[Category: Wood | [[Category: Wood CM]] | ||