1oat: Difference between revisions
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<StructureSection load='1oat' size='340' side='right'caption='[[1oat]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1oat' size='340' side='right'caption='[[1oat]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1oat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OAT FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oat OCA], [https://pdbe.org/1oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oat RCSB], [https://www.ebi.ac.uk/pdbsum/1oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oat ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oat OCA], [https://pdbe.org/1oat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oat RCSB], [https://www.ebi.ac.uk/pdbsum/1oat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oat ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/OAT_HUMAN OAT_HUMAN] Defects in OAT are the cause of hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:[https://omim.org/entry/258870 258870]. HOGA is a slowly progressive blinding autosomal recessive disorder.<ref>PMID:3375240</ref> <ref>PMID:2793865</ref> <ref>PMID:1612597</ref> <ref>PMID:1737786</ref> <ref>PMID:7887415</ref> <ref>PMID:7668253</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OAT_HUMAN OAT_HUMAN] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Jansonius JN]] | |||
[[Category: Jansonius | [[Category: Schirmer T]] | ||
[[Category: Schirmer | [[Category: Shen BW]] | ||
[[Category: Shen | |||