2ntk: Difference between revisions

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<StructureSection load='2ntk' size='340' side='right'caption='[[2ntk]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
<StructureSection load='2ntk' size='340' side='right'caption='[[2ntk]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ntk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NTK FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ntk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NTK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ntl|2ntl]], [[2ntm|2ntm]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PurO ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 "Methanobacterium thermoautotrophicus" (sic) Zeikus and Wolfe 1972])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/IMP_cyclohydrolase IMP cyclohydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.10 3.5.4.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ntk OCA], [https://pdbe.org/2ntk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ntk RCSB], [https://www.ebi.ac.uk/pdbsum/2ntk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ntk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ntk OCA], [https://pdbe.org/2ntk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ntk RCSB], [https://www.ebi.ac.uk/pdbsum/2ntk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ntk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PURO_METTH PURO_METTH]] Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP (By similarity).  
[https://www.uniprot.org/uniprot/PURO_METTH PURO_METTH] Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: IMP cyclohydrolase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ealick, S E]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Kang, Y N]]
[[Category: Ealick SE]]
[[Category: Tran, A]]
[[Category: Kang YN]]
[[Category: White, R H]]
[[Category: Tran A]]
[[Category: Alpha-beta-beta-alpha ntn hydrolase fold]]
[[Category: White RH]]
[[Category: Hydrolase]]

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