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==Crystal Structure of 5-chloroindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C== | ==Crystal Structure of 5-chloroindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C== | ||
<StructureSection load='6yyf' size='340' side='right'caption='[[6yyf]]' scene=''> | <StructureSection load='6yyf' size='340' side='right'caption='[[6yyf]], [[Resolution|resolution]] 1.93Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YYF FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YYF FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yyf OCA], [https://pdbe.org/6yyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yyf RCSB], [https://www.ebi.ac.uk/pdbsum/6yyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yyf ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3IS:5-chloranyl-1,3-dihydroindol-2-one'>3IS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yyf OCA], [https://pdbe.org/6yyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yyf RCSB], [https://www.ebi.ac.uk/pdbsum/6yyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yyf ProSAT]</span></td></tr> | |||
</table> | </table> | ||
==See Also== | |||
*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 08:59, 21 November 2024
Crystal Structure of 5-chloroindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28CCrystal Structure of 5-chloroindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C
Structural highlights
See Also |
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