1j3c: Difference between revisions

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==Solution structure of the C-terminal domain of the HMGB2==
==Solution structure of the C-terminal domain of the HMGB2==
<StructureSection load='1j3c' size='340' side='right'caption='[[1j3c]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='1j3c' size='340' side='right'caption='[[1j3c]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3C FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3C FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [https://pdbe.org/1j3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [https://www.ebi.ac.uk/pdbsum/1j3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3c ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [https://pdbe.org/1j3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [https://www.ebi.ac.uk/pdbsum/1j3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity).  
[https://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pig]]
[[Category: Sus scrofa]]
[[Category: Kurita, J]]
[[Category: Kurita J]]
[[Category: Shimahara, H]]
[[Category: Shimahara H]]
[[Category: Tate, S]]
[[Category: Tate S]]
[[Category: Yoshida, M]]
[[Category: Yoshida M]]
[[Category: Dna binding protein]]
[[Category: Hmg-box]]

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