2k0r: Difference between revisions

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==Solution structure of the C103S mutant of the N-terminal Domain of DsbD from Neisseria meningitidis==
==Solution structure of the C103S mutant of the N-terminal Domain of DsbD from Neisseria meningitidis==
<StructureSection load='2k0r' size='340' side='right'caption='[[2k0r]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2k0r' size='340' side='right'caption='[[2k0r]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k0r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimi Neimi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0R FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k0r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_B Neisseria meningitidis serogroup B]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0R FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dsbD, NMB1519 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0r OCA], [https://pdbe.org/2k0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0r RCSB], [https://www.ebi.ac.uk/pdbsum/2k0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0r OCA], [https://pdbe.org/2k0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0r RCSB], [https://www.ebi.ac.uk/pdbsum/2k0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DSBD_NEIMB DSBD_NEIMB]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).  
[https://www.uniprot.org/uniprot/DSBD_NEIMB DSBD_NEIMB] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Neimi]]
[[Category: Neisseria meningitidis serogroup B]]
[[Category: Protein-disulfide reductase]]
[[Category: Averlant-Petit M]]
[[Category: Averlant-Petit, M]]
[[Category: Beaufils C]]
[[Category: Beaufils, C]]
[[Category: Boschi-Muller S]]
[[Category: Boschi-Muller, S]]
[[Category: Branlant G]]
[[Category: Branlant, G]]
[[Category: Cung M]]
[[Category: Cung, M]]
[[Category: Jacob C]]
[[Category: Jacob, C]]
[[Category: Quinternet M]]
[[Category: Quinternet, M]]
[[Category: Selme L]]
[[Category: Selme, L]]
[[Category: Tsan P]]
[[Category: Tsan, P]]
[[Category: Cytochrome c-type biogenesis]]
[[Category: Disulfide bond reductase]]
[[Category: Electron transport]]
[[Category: Immunoglobulin]]
[[Category: Inner membrane]]
[[Category: Membrane]]
[[Category: Mutant]]
[[Category: N-terminal domain]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Redox-active center]]
[[Category: Transmembrane]]
[[Category: Transport]]

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