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==Crystal structure of MAT2a with triazinone fragment 1 bound in the allosteric site== | |||
<StructureSection load='7bhr' size='340' side='right'caption='[[7bhr]], [[Resolution|resolution]] 1.08Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7bhr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=TQE:4-(dimethylamino)-6-ethoxy-1~{H}-1,3,5-triazin-2-one'>TQE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bhr OCA], [https://pdbe.org/7bhr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bhr RCSB], [https://www.ebi.ac.uk/pdbsum/7bhr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bhr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | |||
==See Also== | |||
*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Argyrou A]] | |||
[[Category: Bagal S]] | |||
[[Category: Borjesson U]] | |||
[[Category: Cheung T]] | |||
[[Category: Chiarparin E]] | |||
[[Category: Collie I]] | |||
[[Category: De Fusco C]] | |||
[[Category: Evans L]] | |||
[[Category: Grondine M]] | |||
[[Category: Narasimhan P]] | |||
[[Category: Robb G]] | |||
[[Category: Schimpl M]] | |||
[[Category: Scott JS]] | |||
[[Category: Stubbs C]] | |||
[[Category: Tentarelli S]] | |||
[[Category: Underwood E]] | |||
[[Category: Vazquez-Chantada M]] | |||
[[Category: Wagner DJ]] | |||
Latest revision as of 10:48, 1 May 2024
Crystal structure of MAT2a with triazinone fragment 1 bound in the allosteric siteCrystal structure of MAT2a with triazinone fragment 1 bound in the allosteric site
Structural highlights
FunctionMETK2_HUMAN Catalyzes the formation of S-adenosylmethionine from methionine and ATP. See Also |
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