5s9c: Difference between revisions

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-'''Unreleased structure'''
-The entry 5s9c is ON HOLD
+==PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative==
+<StructureSection load='5s9c' size='340' side='right'caption='[[5s9c]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5s9c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5S9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5S9C FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y0D:N-(cyclopropylmethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide'>Y0D</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5s9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5s9c OCA], [https://pdbe.org/5s9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5s9c RCSB], [https://www.ebi.ac.uk/pdbsum/5s9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5s9c ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>
-Authors: Grosjean, H., Aimon, A., Hassel-Hart , S., Krojer, T., Talon, R., Douangamath, A., Koekemoer, L., Biggin, P.C., Spencer, J., von Delft, F.
+==See Also==
+*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
-Description: PanDDA analysis group deposition --Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Spencer, J]]
+__TOC__
-[[Category: Aimon, A]]
+</StructureSection>
-[[Category: Grosjean, H]]
+[[Category: Homo sapiens]]
-[[Category: Biggin, P.C]]
+[[Category: Large Structures]]
-[[Category: Hassel-Hart , S]]
+[[Category: Aimon A]]
-[[Category: Talon, R]]
+[[Category: Biggin PC]]
-[[Category: Douangamath, A]]
+[[Category: Douangamath A]]
-[[Category: Krojer, T]]
+[[Category: Grosjean H]]
-[[Category: Von Delft, F]]
+[[Category: Hassel-Hart S]]
-[[Category: Koekemoer, L]]
+[[Category: Koekemoer L]]
+[[Category: Krojer T]]
+[[Category: Spencer J]]
+[[Category: Talon R]]
+[[Category: Von Delft F]]