Regulatory protein E2: Difference between revisions
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<StructureSection load='2ayg' size='340' side='right' caption='Human papillomavirus 6a regulatory protein E2 complex with DNA (PDB code [[2ayg]])' scene=''> | <StructureSection load='2ayg' size='340' side='right' caption='Human papillomavirus 6a regulatory protein E2 complex with DNA (PDB code [[2ayg]])' scene='87/873776/Cv/2'> | ||
==Function== | ==Function== | ||
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== Structural highlights == | == Structural highlights == | ||
The complex between HPV6a DBD and 18-bp DNA (PDB code [[2ayg]]) shows the binding of 2 recognition helices of the dimer to 2 successive major grooves of the target DNA making numerous contacts to the DNA backbone phosphate atoms and to its bases<ref>PMID:16914454</ref>. | <scene name='87/873776/Cv/3'>The complex between HPV6a DBD and 18-bp DNA</scene> (PDB code [[2ayg]]) shows the binding of 2 recognition helices of the dimer to 2 successive major grooves of the target DNA making numerous contacts to the DNA backbone phosphate atoms and to its bases<ref>PMID:16914454</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of regulatory protein E2== | ==3D structures of regulatory protein E2== | ||
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[[3mi7]] - RPE2 DBD (mutant)<br /> | [[3mi7]] - RPE2 DBD (mutant)<br /> | ||
[[1r8p]], [[1zzf]] - RPE2 DBD - NMR<br /> | [[1r8p]], [[1zzf]] - RPE2 DBD - NMR<br /> | ||
[[1tue]] - RPE2 TAD + | [[1tue]] - RPE2 TAD + RPE1 - HPV18<br /> | ||
[[1qqh]] - RPE2 TAD<br /> | [[1qqh]] - RPE2 TAD<br /> | ||
[[1f9f]] - RPE2 DBD<br /> | [[1f9f]] - RPE2 DBD<br /> | ||