Nuclear receptor: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 5: Line 5:
</ref>
</ref>


== Structure ==
SEE [[Nuclear receptors]]
 
=== DBD (DNA Binding Domain) ===
=== LBD (Ligand Binding Domain) ===
<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''>
<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''>


Line 19: Line 16:


</StructureSection>
</StructureSection>
'''Family members:'''
* [[Androgen receptor]]
* '''Estrogen Receptor-like'''
** [[Estrogen receptor]]
** [[Estrogen-related receptor]]
* [[Peroxisome Proliferator-Activated Receptors]]
* [[Vitamin D receptor]]


<references/>
<references/>

Latest revision as of 19:36, 25 January 2021

the nuclear receptors facts book [1]

SEE Nuclear receptors


The structure of the LBD is strongly conserved throughout the familly of nuclear receptors. It is a globular domain, mainly alpha composed of arranged in a three layered sandwich, and a .


Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry 1ie8)

Drag the structure with the mouse to rotate
  1. Vincent Laudet, Hinrich Gronemeyer, "The nuclear receptor factsbook", Publisher Academic Press, 2002

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Schwarz Benjamin, Alexander Berchansky