7dox: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 7dox is ON HOLD  until Dec 17 2022
==The structure of the Arabidopsis thaliana guanosine deaminase in complex with m7G==
<StructureSection load='7dox' size='340' side='right'caption='[[7dox]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7dox]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG7:7-METHYLGUANOSINE'>MG7</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dox OCA], [https://pdbe.org/7dox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dox RCSB], [https://www.ebi.ac.uk/pdbsum/7dox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dox ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSDA_ARATH GSDA_ARATH] Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia. Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines. Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.<ref>PMID:24130159</ref>


Authors: Xie, W., Jia, Q., Zeng, H.
==See Also==
 
*[[Deaminase 3D structures|Deaminase 3D structures]]
Description: The structure of the Arabidopsis thaliana guanosine deaminase in complex with m7G
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Xie, W]]
__TOC__
[[Category: Jia, Q]]
</StructureSection>
[[Category: Zeng, H]]
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Jia Q]]
[[Category: Xie W]]
[[Category: Zeng H]]

Latest revision as of 19:37, 29 November 2023

The structure of the Arabidopsis thaliana guanosine deaminase in complex with m7GThe structure of the Arabidopsis thaliana guanosine deaminase in complex with m7G

Structural highlights

7dox is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GSDA_ARATH Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia. Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines. Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.[1]

See Also

References

  1. ↑ Dahncke K, Witte CP. Plant purine nucleoside catabolism employs a guanosine deaminase required for the generation of xanthosine in Arabidopsis. Plant Cell. 2013 Oct;25(10):4101-9. doi: 10.1105/tpc.113.117184. Epub 2013 Oct, 15. PMID:24130159 doi:http://dx.doi.org/10.1105/tpc.113.117184

7dox, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=7dox&oldid=3969349"