6ib6: Difference between revisions

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==Solution structure of the water-soluble LU-domain of human Lypd6 protein==
==Solution structure of the water-soluble LU-domain of human Lypd6 protein==
<StructureSection load='6ib6' size='340' side='right'caption='[[6ib6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='6ib6' size='340' side='right'caption='[[6ib6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ib6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IB6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6IB6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ib6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IB6 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LYPD6, UNQ3023/PRO9821 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ib6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ib6 OCA], [http://pdbe.org/6ib6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ib6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ib6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ib6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ib6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ib6 OCA], [https://pdbe.org/6ib6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ib6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ib6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ib6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LYPD6_HUMAN LYPD6_HUMAN]] Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs (PubMed:27344019). Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity).[UniProtKB:Q66IA6]<ref>PMID:27344019</ref>
[https://www.uniprot.org/uniprot/LYPD6_HUMAN LYPD6_HUMAN] Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs (PubMed:27344019). Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity).[UniProtKB:Q66IA6]<ref>PMID:27344019</ref>  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kulbatskii, D S]]
[[Category: Kulbatskii DS]]
[[Category: Lyukmanova, E N]]
[[Category: Lyukmanova EN]]
[[Category: Paramonov, A S]]
[[Category: Paramonov AS]]
[[Category: Shenkarev, Z O]]
[[Category: Shenkarev ZO]]
[[Category: Tsarev, A V]]
[[Category: Tsarev AV]]
[[Category: Ly6/upar]]
[[Category: Lypd6]]
[[Category: Neuropeptide]]
[[Category: Nicotinic acetylcholine receptor]]
[[Category: Signaling protein]]
[[Category: Three-finger protein]]

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