1s70: Difference between revisions

<table><tr><td colspan='2'>[[1s70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S70 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1S70 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fjm|1fjm]], [[1it6|1it6]], [[1jk7|1jk7]]</div></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPP1CB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1s70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s70 OCA], [http://pdbe.org/1s70 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s70 RCSB], [http://www.ebi.ac.uk/pdbsum/1s70 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s70 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PP1B_HUMAN PP1B_HUMAN]] Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.<ref>PMID:20516061</ref>  [[http://www.uniprot.org/uniprot/MYPT1_CHICK MYPT1_CHICK]] Regulates myosin phosphatase activity.<ref>PMID:7982954</ref> 

[[Category: Chick]]

[[Category: Human]]

[[Category: Dominguez, R]]

[[Category: Kerff, F]]

[[Category: Terrak, M]]

[[Category: Pp1]]