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==Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47== | |||
<StructureSection load='7aab' size='340' side='right'caption='[[7aab]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AAB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UHB:2-[4-[(2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]CARBONYLPIPERAZIN-1-YL]-N-(1-OXIDANYLIDENE-2,3-DIHYDROISOINDOL-4-YL)ETHANAMIDE'>UHB</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7aab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7aab OCA], [https://pdbe.org/7aab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7aab RCSB], [https://www.ebi.ac.uk/pdbsum/7aab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7aab ProSAT]</span></td></tr> | |||
</table> | |||
==See Also== | |||
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Easton LE]] | |||
[[Category: Embrey KJ]] | |||
[[Category: Johannes JW]] | |||
[[Category: Neuhaus D]] | |||
[[Category: Ogden TEH]] | |||
[[Category: Rawlins PB]] | |||
[[Category: Schimpl M]] | |||
[[Category: Underwood E]] | |||
[[Category: Yang J-C]] |