7cme: Difference between revisions

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-'''Unreleased structure'''
-The entry 7cme is ON HOLD
+==Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)==
+<StructureSection load='7cme' size='340' side='right'caption='[[7cme]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7cme]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CME FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=G60:2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine'>G60</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cme OCA], [https://pdbe.org/7cme PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cme RCSB], [https://www.ebi.ac.uk/pdbsum/7cme PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cme ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CADH3_HUMAN CADH3_HUMAN] Hypotrichosis with juvenile macular degeneration;EEM syndrome. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/CADH3_HUMAN CADH3_HUMAN] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
-Authors: Senoo, A., Ito, S., Ueno, G., Nagatoishi, S., Tsumoto, K.
+==See Also==
+*[[Cadherin 3D structures|Cadherin 3D structures]]
-Description: Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Nagatoishi, S]]
+[[Category: Homo sapiens]]
-[[Category: Tsumoto, K]]
+[[Category: Large Structures]]
-[[Category: Senoo, A]]
+[[Category: Ito S]]
-[[Category: Ito, S]]
+[[Category: Nagatoishi S]]
-[[Category: Ueno, G]]
+[[Category: Senoo A]]
+[[Category: Tsumoto K]]
+[[Category: Ueno G]]