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==Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001== | |||
<StructureSection load='7a2a' size='340' side='right'caption='[[7a2a]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A2A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=57N:(2R)-2-(1-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-2-PHENYL-N-(1,3-THIAZOL-2-YL)ACETAMIDE'>57N</scene>, <scene name='pdbligand=7G9:~{N}-[3-[[5-FLUORANYL-2-[[4-(2-METHOXYETHOXY)PHENYL]AMINO]PYRIMIDIN-4-YL]AMINO]PHENYL]PROPANAMIDE'>7G9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a2a OCA], [https://pdbe.org/7a2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a2a RCSB], [https://www.ebi.ac.uk/pdbsum/7a2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a2a ProSAT]</span></td></tr> | |||
</table> | |||
==See Also== | |||
*[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mueller MP]] | ||
[[Category: Rauh | [[Category: Niggenaber J]] | ||
[[Category: Rauh D]] | |||
Latest revision as of 16:23, 6 November 2024
Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001
Structural highlights
See Also |
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