3anx: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 3: Line 3:
<StructureSection load='3anx' size='340' side='right'caption='[[3anx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3anx' size='340' side='right'caption='[[3anx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3anx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ANX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3ANX FirstGlance]. <br>
<table><tr><td colspan='2'>[[3anx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ANX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ANX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3anx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3anx OCA], [http://pdbe.org/3anx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3anx RCSB], [http://www.ebi.ac.uk/pdbsum/3anx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3anx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3anx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3anx OCA], [https://pdbe.org/3anx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3anx RCSB], [https://www.ebi.ac.uk/pdbsum/3anx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3anx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPEE_THET8 SPEE_THET8]] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.<ref>PMID:21458463</ref>
[https://www.uniprot.org/uniprot/SPEE_THET8 SPEE_THET8] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.<ref>PMID:21458463</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 27:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Spermidine synthase]]
[[Category: Thermus thermophilus HB8]]
[[Category: Thet8]]
[[Category: Ganbe T]]
[[Category: Ganbe, T]]
[[Category: Kumasaka T]]
[[Category: Kumasaka, T]]
[[Category: Ohnuma M]]
[[Category: Ohnuma, M]]
[[Category: Oshima T]]
[[Category: Oshima, T]]
[[Category: Sato T]]
[[Category: Sato, T]]
[[Category: Tanaka N]]
[[Category: Tanaka, N]]
[[Category: Polyamine]]
[[Category: Spee]]
[[Category: Spermidine biosynthesis]]
[[Category: Spermine synthase]]
[[Category: Transferase-transferase inhibitor complex]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA