FKBP 3D structures: Difference between revisions
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Michal Harel (talk | contribs) New page: == 3D Structures of FKBP == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *FKBP **1fkr, 1fks, 1fkt ... |
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**[[1bkf]] – hFKBP (mutant)+FK-506<br /> | **[[1bkf]] – hFKBP (mutant)+FK-506<br /> | ||
**[[1fkf]] - hFKBP+FK-506<br /> | **[[1fkf]] - hFKBP+FK-506<br /> | ||
**[[7dki]] – FKBP - silk worm<br /> | |||
**[[1fks]], [[1fkr]], [[1fkt]] – EcFKBP – ''Escherichia coli''<br /> | **[[1fks]], [[1fkr]], [[1fkt]] – EcFKBP – ''Escherichia coli''<br /> | ||
**[[1q6h]], [[1q6u]] – EcFKBP<br /> | **[[1q6h]], [[1q6u]] – EcFKBP<br /> | ||
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*FKBP1 | *FKBP1 | ||
**[[4iq2]], [[4iqc]] - hFKBP-1B (mutant)<br /> | **[[4iq2]], [[4iqc]] - hFKBP-1B (mutant)<br /> | ||
**[[4c02]] - hFKBP-1B+ activin receptor type I<br /> | **[[4c02]] - hFKBP-1B+ activin receptor type I<br /> | ||
**[[5tap]], [[6jgz]], [[6jh6]], [[6jhn]], [[6ji0]], [[6jrr]], [[6pv6]], [[6w1n]], [[6wot]], [[6wou]], [[6wov]], [[6x34]], [[7cf9]], [[7jmf]], [[7jmg]], [[7jmh]], [[7jmi]], [[7jmj]] - hFKBP-1B + ryanodine receptor type I – Cryo EM<br /> | |||
**[[6ji8]], [[6jii]], [[6jiu]], [[6jiy]], [[6jrs]], [[6m2w]], [[6x32]], [[6x33]], [[6x35]], [[6x36]] - hFKBP-1B + ryanodine receptor type I + calmodulin 1 – Cryo EM<br /> | |||
*FKBP3 | *FKBP3 | ||
**[[3kz7]] – hFKBP FK506-binding domain + immunosuppressant - human | **[[3kz7]] – hFKBP FK506-binding domain + immunosuppressant - human | ||
*FKBP8 | *FKBP8 | ||
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**[[2mf9]] – hFKBP N terminal 58-206 – NMR<br /> | **[[2mf9]] – hFKBP N terminal 58-206 – NMR<br /> | ||
*FKBP12 | *FKBP12 or PPIase FKBP1A | ||
**[[1fkk]], [[2ppp]], [[2ppn]], [[2dg3]], [[1d6o]] – hFKBP<br /> | **[[1fkk]], [[2ppp]], [[2ppn]], [[2dg3]], [[1d6o]] – hFKBP<br /> | ||
**[[1eym]], [[2ppo]], [[4ipx]] – hFKBP (mutant) <br /> | **[[1eym]], [[2ppo]], [[4ipx]], [[4n19]] – hFKBP (mutant) <br /> | ||
**[[2gaq]], [[2pnu]] – hFKBP - NMR<br /> | **[[2gaq]], [[2pnu]] – hFKBP - NMR<br /> | ||
**[[3uqi]] – ymFKBP – yellowfever mosquito<br /> | **[[3uqi]] – ymFKBP – yellowfever mosquito<br /> | ||
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**[[5hwb]] – NfFKBP – ''Neosartorya fumigata''<br /> | **[[5hwb]] – NfFKBP – ''Neosartorya fumigata''<br /> | ||
**[[5j6e]] – NfFKBP (mutant) <br /> | **[[5j6e]] – NfFKBP (mutant) <br /> | ||
**[[6vsi]] – FKBP – ''Candida auris'' <br /> | |||
*FKBP12 complex | *FKBP12 complex | ||
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**[[4fap]] - hFKBP + FKBP12-rapamycin associated protein + immunosuppressant<br /> | **[[4fap]] - hFKBP + FKBP12-rapamycin associated protein + immunosuppressant<br /> | ||
**[[2dg4]], [[1fkb]], [[1c9h]], [[4dh0]] - hFKBP+rapamycin<br /> | **[[2dg4]], [[1fkb]], [[1c9h]], [[4dh0]] - hFKBP+rapamycin<br /> | ||
**[[2dg9]] - hFKBP (mutant)+rapamycin<br /> | **[[2dg9]], [[7u8d]] - hFKBP (mutant)+rapamycin<br /> | ||
**[[2fap]], [[1nsg]], [[1fap]] - hFKBP+rapamycin+FRB<br /> | **[[2fap]], [[1nsg]], [[1fap]] - hFKBP+rapamycin+FRB<br /> | ||
**[[1f40]] – hFKBP +GPI-1046<br /> | **[[1f40]] – hFKBP +GPI-1046<br /> | ||
**[[1a7x]] – hFKBP +FK-1012<br /> | **[[1a7x]] – hFKBP +FK-1012<br /> | ||
**[[1d7h]], [[1d7i]], [[1d7j]], [[1fkg]], [[1fkh]], [[1fki]] – hFKBP +ligand<br /> | **[[1d7h]], [[1d7i]], [[1d7j]], [[1fkg]], [[1fkh]], [[1fki]] – hFKBP +ligand<br /> | ||
**[[6vcu]], [[6yf0]], [[6yf1]], [[6yf2]], [[6yf3]] – hFKBP + drug<br /> | |||
**[[8er6]], [[8er7]] – hFKBP + serine/threonine protein kinase 224-317 + inhibitor<br /> | |||
**[[6m4u]] – hFKBP + serine/threonine protein kinase MTOR peptide <br /> | |||
**[[2rse]] – hFKBP + serine/threonine protein kinase MTOR peptide + rapamycin - NMR<br /> | **[[2rse]] – hFKBP + serine/threonine protein kinase MTOR peptide + rapamycin - NMR<br /> | ||
**[[6m4v]], [[6m4w]] – hFKBP + MBP + rapamycin<br /> | |||
**[[3h9r]], [[6i1s]] – hFKBP + activin receptor type I<br /> | |||
**[[3mdy]] – hFKBP+ BMPR1B<br /> | |||
**[[1j4r]] – hFKBP + FKB-001<br /> | |||
**[[6oqa]] - hFKBP+ CEP250<br /> | |||
**[[7m6a]], [[7m6l]], [[7vmm]], [[7vmn]], [[7vml]], [[7vmo]], [[7vmp]], [[7vmq]], [[7vmr]], [[7vms]], [[7u0s]], [[7u8d]], [[7u9q]], [[7u9r]], [[7u9t]], [[7u9x]], [[7u9z]], [[7ua1]], [[7ua3]], [[7ua4]], [[7ua5]], [[7ua9]] - hFKBP + ryanodine receptor type 2 – Cryo EM<br /> | |||
**[[1tco]] - bFKBP + Ser/Thr phosphatase B2 + immunosuppressant - bovine<br /> | **[[1tco]] - bFKBP + Ser/Thr phosphatase B2 + immunosuppressant - bovine<br /> | ||
**[[1fkl]] – bFKBP +rapamycin <br /> | **[[1fkl]] – bFKBP +rapamycin <br /> | ||
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**[[5hw8]] – CaFKBP (mutant) + FK506<br /> | **[[5hw8]] – CaFKBP (mutant) + FK506<br /> | ||
**[[6tz6]] – CaFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase<br /> | **[[6tz6]] – CaFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase<br /> | ||
**[[6vcv]] - NfFKBP + FK506 analog <br /> | |||
**[[5hwc]] – NfFKBP (mutant) + FK506<br /> | **[[5hwc]] – NfFKBP (mutant) + FK506<br /> | ||
**[[6tz7]] – NfFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase<br /> | **[[6tz7]] – NfFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase<br /> | ||
**[[6tz8]] – FKBP + FK506 + calcineurin B + serine/threonine protein phosphatase – ''Cryptococcus neoformans''<br /> | **[[6tz8]] – FKBP + FK506 + calcineurin B + serine/threonine protein phosphatase – ''Cryptococcus neoformans''<br /> | ||
**[[6vct]], [[6vrx]] – FKBP + FK506 analog – ''Mucor circinelloides''<br /> | |||
*FKBP12.6 | *FKBP12.6 | ||
**[[5hkg]] – hFKBP <br /> | **[[5hkg]] – hFKBP <br /> | ||
**[[7t64]], [[7t65]], [[7tzc]] - rFKBP + ryanodine receptor type 1 – Cryo EM<br /> | |||
*FKBP13 | *FKBP13 | ||
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**[[2if4]] – AtFKBP <br /> | **[[2if4]] – AtFKBP <br /> | ||
*FKBP51 | *FKBP51 or PPIase FKBP5; Domains – FK1 1-140; FK2 141-260 | ||
**[[ | **[[5omp]], [[1kt1]] – hFKBP<br /> | ||
**[[4r0x]] – hFKBP FK1 domain (mutant) <br /> | **[[1kt0]] – hFKBP (mutant)<br /> | ||
**[[4drq]] – hFKBP FK1 domain + | **[[5njx]] – hFKBP + Hsp90 peptide<br /> | ||
**[[4jfi]], [[4jfj]], [[4jfk]], [[4jfl]], [[4jfm]], [[4tw6]], [[4tw7]], [[4tx0]], [[4w9o]], [[4w9p]], [[4w9q]], [[5dit]], [[5diu]], [[5div]] – hFKBP FK1 domain (mutant) + inhibitor<br /> | **[[7l7i]] – hFKBP + Hsp90 + P23 – Cryo EM<br /> | ||
**[[3o5d]] – hFKBP FK1+FK2 domains <br /> | |||
**[[3o5e]], [[3o5f]], [[3o5g]], [[3o5i]], [[3o5j]], [[3o5k]] - hFKBP FK1 domain<br /> | |||
**[[3o5l]], [[3o5m]], [[3o5o]], [[3o5p]], [[3o5q]], [[4r0x]] - hFKBP FK1 domain (mutant)<br /> | |||
**[[4lax]] – hFKBP FK1+FK2 domains + FK506<br /> | |||
**[[4lay]] – hFKBP FK1+FK2 domains + I63<br /> | |||
**[[3o5r]] - hFKBP FK1 domain (mutant) + immunosuppressant<br /> | |||
**[[4drk]], [[4drm]], [[4drn]], [[4dro]], [[4drp]] – hFKBP FK1 domain + FK506 analog<br /> | |||
**[[4drq]], [[5obk]], [[7a6w]], [[7a6x]], [[7aot]], [[7aou]], [[7apq]], [[7aps]], [[7apt]], [[7apw]], [[7awf]], [[7awx]], [[7b9y]], [[7b9z]], [[7ba0]] – hFKBP FK1 domain + inhibitor<br /**[[7a6w]], [[7a6x]], [[7aot]], [[7aou]], [[7awf]], [[7awx]], [[7b9y]], [[7b9z]], [[7ba0]] – hFKBP FK1 domain + inhibitor<br /> | |||
**[[4jfi]], [[4jfj]], [[4jfk]], [[4jfl]], [[4jfm]], [[4tw6]], [[4tw7]], [[4tx0]], [[4w9o]], [[4w9p]], [[4w9q]], [[5dit]], [[5diu]], [[5div]], [[7r0l]], [[8ba6]], [[8baj]] – hFKBP FK1 domain (mutant) + inhibitor<br /> | |||
**[[7ett]], [[7etu]], [[7etv]] – hFKBP FK1 domain (mutant) + peptide inhibitor<br /> | |||
**[[5bxj]] – hFKBP FK1 domain (mutant) + nitrophenol<br /> | **[[5bxj]] – hFKBP FK1 domain (mutant) + nitrophenol<br /> | ||
**[[4tw8]] – hFKBP FK1+FK2 domains (mutant) + inhibitor<br /> | **[[4tw8]] – hFKBP FK1+FK2 domains (mutant) + inhibitor<br /> | ||
**[[4drk]], [[4drm]], [[4drn]], [[4dro]], [[4drp]] – hFKBP FK1 domain + FK506 analog<br /> | **[[4drk]], [[4drm]], [[4drn]], [[4dro]], [[4drp]] – hFKBP FK1 domain + FK506 analog<br /> | ||
**[[8era]] – hFKBP FK1 domain + serine/threonine protein kinase MTOR + TORC + raptor – Cryo EM <br /> | |||
**[[4drh]], [[4dri]] – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin <br /> | **[[4drh]], [[4dri]] – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin <br /> | ||
**[[6tx4]] – hFKBP FK1 domain + pyridone<br /> | |||
**[[6tx6]] – hFKBP FK1 domain + nicotinamide<br /> | |||
**[[6tx5]], [[6tx8]] – hFKBP FK1 domain (mutant) + imidazole derivative<br /> | |||
**[[6tx7]] – hFKBP FK1 domain (mutant) + piperidone derivative<br /> | |||
**[[6tx9]] – hFKBP FK1 domain (mutant) + hydantoin derivative<br /> | |||
**[[6saf]], [[6txx]] – hFKBP FK1 domain (mutant) + ligand<br /> | |||
*FKBP52 | *FKBP52 or PPIase FKBP4 | ||
**[[4lav]], [[4law]] – hFKBP FK1+FK2 domains 16-260<br /> | |||
**[[1n1a]], [[1q1c]] – hFKBP N terminal 1-140<br /> | |||
**[[1p5q]] - hFKBP C terminal 144-458<br /> | |||
**[[4drj]] – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin <br /> | **[[4drj]] – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin <br /> | ||
**[[6rcy]] – hFKBP FK1 domain + ligand<br /> | |||
**[[1qz2]] – hFKBP C-terminal + Hsp90 peptide<br /> | |||
*FKBP59 | *FKBP59 | ||
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See [[Peptidyl-prolyl cis-trans isomerase]] | See [[Peptidyl-prolyl cis-trans isomerase]] | ||
}} | }} | ||
[[Category: Topic Page]] |
Latest revision as of 14:33, 5 March 2023
3D Structures of FKBP3D Structures of FKBP
Updated on 05-March-2023