2xs6: Difference between revisions
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<StructureSection load='2xs6' size='340' side='right'caption='[[2xs6]], [[Resolution|resolution]] 2.09Å' scene=''> | <StructureSection load='2xs6' size='340' side='right'caption='[[2xs6]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xs6]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2xs6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XS6 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xs6 OCA], [https://pdbe.org/2xs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xs6 RCSB], [https://www.ebi.ac.uk/pdbsum/2xs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xs6 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/P85B_HUMAN P85B_HUMAN] Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Berglund H]] | |||
[[Category: Berglund | [[Category: Bountra C]] | ||
[[Category: Bountra | [[Category: Collins R]] | ||
[[Category: Collins | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Flodin S]] | ||
[[Category: Flodin | [[Category: Flores A]] | ||
[[Category: Flores | [[Category: Graslund S]] | ||
[[Category: Graslund | [[Category: Hammarstrom M]] | ||
[[Category: Hammarstrom | [[Category: Johansson I]] | ||
[[Category: Johansson | [[Category: Karlberg T]] | ||
[[Category: Karlberg | [[Category: Kol S]] | ||
[[Category: Kol | [[Category: Kotenyova T]] | ||
[[Category: Kotenyova | [[Category: Kouznetsova E]] | ||
[[Category: Kouznetsova | [[Category: Moche M]] | ||
[[Category: Moche | [[Category: Nordlund P]] | ||
[[Category: Nordlund | [[Category: Nyman T]] | ||
[[Category: Nyman | [[Category: Persson C]] | ||
[[Category: Persson | [[Category: Schuler H]] | ||
[[Category: Schuler | [[Category: Schutz P]] | ||
[[Category: Schutz | [[Category: Siponen MI]] | ||
[[Category: Siponen | [[Category: Thorsell AG]] | ||
[[Category: Thorsell | [[Category: Tresaugues L]] | ||
[[Category: Tresaugues | [[Category: Wahlberg E]] | ||
[[Category: Wahlberg | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Welin M]] | ||
[[Category: Welin | [[Category: Van der Berg S]] | ||
[[Category: | |||