6rv4: Difference between revisions

<table><tr><td colspan='2'>[[6rv4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RV4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RV4 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=KKZ:[4-[[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-[6-(trifluoromethyloxy)pyridin-2-yl]methanone'>KKZ</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCNK3, TASK, TASK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rv4 OCA], [http://pdbe.org/6rv4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rv4 RCSB], [http://www.ebi.ac.uk/pdbsum/6rv4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rv4 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/KCNK3_HUMAN KCNK3_HUMAN]] Heritable pulmonary arterial hypertension. The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/KCNK3_HUMAN KCNK3_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.<ref>PMID:23169818</ref> <ref>PMID:9312005</ref>

[[Category: Human]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Burgess-Brown, N]]

[[Category: Bushell, S R]]

[[Category: Carpenter, E P]]

[[Category: Chalk, R]]

[[Category: Edwards, A M]]

[[Category: Mukhopadhyay, S M.M]]

[[Category: Pike, A C.W]]

[[Category: Quigley, A]]

[[Category: Rodstrom, K E.J]]

[[Category: Structural genomic]]

[[Category: Shrestha, L]]

[[Category: Speedman, D]]

[[Category: Tessitore, A]]

[[Category: Venkaya, S]]

[[Category: Zhang, W]]

[[Category: Sgc]]