2v4q: Difference between revisions

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 <StructureSection load='2v4q' size='340' side='right'caption='[[2v4q]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2v4q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4Q OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2V4Q FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2v4q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4Q FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M1G:3-(2-DEOXY-BETA-D-RIBOFURANOSYL)-PYRIDO[5,6-A]-PURINE-10-ONE-5-MONOPHOSPHATE'>M1G</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=M1G:3-(2-DEOXY-BETA-D-RIBOFURANOSYL)-PYRIDO[5,6-A]-PURINE-10-ONE-5-MONOPHOSPHATE'>M1G</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s0m|1s0m]], [[2asl|2asl]], [[2jeg|2jeg]], [[1rys|1rys]], [[2j6t|2j6t]], [[1n56|1n56]], [[2atl|2atl]], [[1jx4|1jx4]], [[2c22|2c22]], [[2va2|2va2]], [[1s97|1s97]], [[2agq|2agq]], [[2jej|2jej]], [[2ago|2ago]], [[2asj|2asj]], [[2asd|2asd]], [[1n48|1n48]], [[1jxl|1jxl]], [[2bq3|2bq3]], [[2j6u|2j6u]], [[2uvu|2uvu]], [[2agp|2agp]], [[2c2r|2c2r]], [[1s0n|1s0n]], [[1s0o|1s0o]], [[2jef|2jef]], [[2uvw|2uvw]], [[2bqr|2bqr]], [[2jei|2jei]], [[2bqu|2bqu]], [[2au0|2au0]], [[1s9f|1s9f]], [[2c28|2c28]], [[2v9w|2v9w]], [[2c2e|2c2e]], [[1ryr|1ryr]], [[2c2d|2c2d]], [[2uvv|2uvv]], [[1s10|1s10]], [[2j6s|2j6s]], [[2br0|2br0]], [[2uvr|2uvr]], [[2va3|2va3]], [[2v4r|2v4r]], [[2v4s|2v4s]], [[2v4t|2v4t]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4q OCA], [https://pdbe.org/2v4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4q RCSB], [https://www.ebi.ac.uk/pdbsum/2v4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4q ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2v4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4q OCA], [http://pdbe.org/2v4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4q RCSB], [http://www.ebi.ac.uk/pdbsum/2v4q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4q ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 36: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: DNA-directed DNA polymerase]]
 [[Category: Large Structures]]
-[[Category: Sulso]]
+[[Category: Saccharolobus solfataricus P2]]
-[[Category: Egli, M]]
+[[Category: Egli M]]
-[[Category: Eoff, R L]]
+[[Category: Eoff RL]]
-[[Category: Guengerich, F P]]
+[[Category: Guengerich FP]]
-[[Category: Marnett, L J]]
+[[Category: Marnett LJ]]
-[[Category: Rizzo, C J]]
+[[Category: Rizzo CJ]]
-[[Category: Stafford, J B]]
+[[Category: Stafford JB]]
-[[Category: Szekely, J]]
+[[Category: Szekely J]]
-[[Category: Cytoplasm]]
-[[Category: Dna adduct]]
-[[Category: Dna damage]]
-[[Category: Dna repair]]
-[[Category: Dna replication]]
-[[Category: Dna-binding]]
-[[Category: Dna-directed dna polymerase]]
-[[Category: Dpo4]]
-[[Category: M1dg]]
-[[Category: Magnesium]]
-[[Category: Metal-binding]]
-[[Category: Mutator protein]]
-[[Category: Nucleotidyltransferase]]
-[[Category: Polymerase]]
-[[Category: Transferase]]