6tbu: Difference between revisions

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<StructureSection load='6tbu' size='340' side='right'caption='[[6tbu]], [[Resolution|resolution]] 3.16&Aring;' scene=''>
<StructureSection load='6tbu' size='340' side='right'caption='[[6tbu]], [[Resolution|resolution]] 3.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6tbu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TBU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TBU FirstGlance]. <br>
<table><tr><td colspan='2'>[[6tbu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TBU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">disp, CG2019 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">disp, CG2019 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tbu OCA], [http://pdbe.org/6tbu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tbu RCSB], [http://www.ebi.ac.uk/pdbsum/6tbu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tbu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tbu OCA], [https://pdbe.org/6tbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tbu RCSB], [https://www.ebi.ac.uk/pdbsum/6tbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tbu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DISP_DROME DISP_DROME]] Segment polarity protein which functions in hedgehog (Hh) signaling. Regulates the trafficking and the release of cholesterol-modified hedgehog protein from cells of the posterior compartment (P cells) and is hence required for the effective production of the Hh signal.<ref>PMID:10619433</ref> <ref>PMID:12372301</ref> <ref>PMID:12586063</ref>   
[[https://www.uniprot.org/uniprot/DISP_DROME DISP_DROME]] Segment polarity protein which functions in hedgehog (Hh) signaling. Regulates the trafficking and the release of cholesterol-modified hedgehog protein from cells of the posterior compartment (P cells) and is hence required for the effective production of the Hh signal.<ref>PMID:10619433</ref> <ref>PMID:12372301</ref> <ref>PMID:12586063</ref>   
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

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