5rk5: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 5rk5 is ON HOLD
+==PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z57478994==
+<StructureSection load='5rk5' size='340' side='right'caption='[[5rk5]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5rk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RK5 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.243&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UVS:5-(methoxymethyl)-1,3,4-thiadiazol-2-amine'>UVS</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rk5 OCA], [https://pdbe.org/5rk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rk5 RCSB], [https://www.ebi.ac.uk/pdbsum/5rk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rk5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>
-Authors: Grosjean, H., Aimon, A., Krojer, T., Talon, R., Douangamath, A., Koekemoer, L., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Biggin, P.C.
+==See Also==
+*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
-Description: PanDDA analysis group deposition --Crystal Structure of PHIP in complex with Z57478994
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Aimon, A]]
+__TOC__
-[[Category: Grosjean, H]]
+</StructureSection>
-[[Category: Biggin, P.C]]
+[[Category: Homo sapiens]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Large Structures]]
-[[Category: Talon, R]]
+[[Category: Aimon A]]
-[[Category: Edwards, A]]
+[[Category: Arrowsmith CH]]
-[[Category: Douangamath, A]]
+[[Category: Biggin PC]]
-[[Category: Krojer, T]]
+[[Category: Bountra C]]
-[[Category: Von Delft, F]]
+[[Category: Douangamath A]]
-[[Category: Bountra, C]]
+[[Category: Edwards A]]
-[[Category: Koekemoer, L]]
+[[Category: Grosjean H]]
+[[Category: Koekemoer L]]
+[[Category: Krojer T]]
+[[Category: Talon R]]
+[[Category: Von Delft F]]