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==Cryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgG== | |||
<StructureSection load='7buf' size='340' side='right'caption='[[7buf]], [[Resolution|resolution]] 6.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7buf]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BUF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.1Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7buf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7buf OCA], [https://pdbe.org/7buf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7buf RCSB], [https://www.ebi.ac.uk/pdbsum/7buf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7buf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/E0WXJ2_9FLAV E0WXJ2_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | |||
==See Also== | |||
*[[Antibody 3D structures|Antibody 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Dengue virus 2]] | ||
[[Category: Kostyuchenko | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chew SV]] | ||
[[Category: | [[Category: Kostyuchenko VA]] | ||
[[Category: | [[Category: Lim XN]] | ||
[[Category: Lok SM]] | |||
[[Category: Ng TS]] | |||
[[Category: Zhang S]] |
Latest revision as of 13:49, 27 March 2024
Cryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgGCryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgG
Structural highlights
FunctionE0WXJ2_9FLAV Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] See Also |
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