6wep: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site== | |||
<StructureSection load='6wep' size='340' side='right'caption='[[6wep]], [[Resolution|resolution]] 2.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6wep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WEP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wep OCA], [https://pdbe.org/6wep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wep RCSB], [https://www.ebi.ac.uk/pdbsum/6wep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wep ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A0S4TER9_CRYHO A0A0S4TER9_CRYHO] Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism.[PIRNR:PIRNR000389] | |||
==See Also== | |||
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Cryptosporidium hominis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Anderson KS]] | ||
[[Category: | [[Category: Czyzyk DJ]] | ||
[[Category: | [[Category: Jorgensen WL]] | ||
[[Category: Kumar VP]] | |||
[[Category: Ruiz VG]] | |||
Latest revision as of 17:23, 18 October 2023
Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS siteCrystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site
Structural highlights
FunctionA0A0S4TER9_CRYHO Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism.[PIRNR:PIRNR000389] See Also |
| ||||||||||||||||||