4d2u: Difference between revisions

<table><tr><td colspan='2'>[[4d2u]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D2U FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2u OCA], [https://pdbe.org/4d2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d2u RCSB], [https://www.ebi.ac.uk/pdbsum/4d2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2u ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/CLPB_ECOLI CLPB_ECOLI]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10982797</ref> <ref>PMID:12624113</ref> <ref>PMID:14640692</ref>  

[[Category: Escherichia coli]]

[[Category: Bukau B]]

[[Category: Carroni M]]

[[Category: Clare DK]]

[[Category: Kopp J]]

[[Category: Kummer E]]

[[Category: Mogk A]]

[[Category: Oguchi Y]]

[[Category: Saibil HR]]

[[Category: Sinning I]]

[[Category: Wendler P]]