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==Crystal structure of an adenine deaminase==
==Crystal structure of an adenine deaminase==
<StructureSection load='2ics' size='340' side='right'caption='[[2ics]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2ics' size='340' side='right'caption='[[2ics]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ics]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ICS FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ICS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ics FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ics OCA], [https://pdbe.org/2ics PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ics RCSB], [https://www.ebi.ac.uk/pdbsum/2ics PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ics ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ics TOPSAN]</span></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenine_deaminase Adenine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.2 3.5.4.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ics FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ics OCA], [http://pdbe.org/2ics PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ics RCSB], [http://www.ebi.ac.uk/pdbsum/2ics PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ics ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2ics TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DEACT_ENTFA DEACT_ENTFA]] Esterase that can catalyze the deacetylation of acetyl-(R)-mandelate, but with very low efficiency (in vitro).<ref>PMID:23214420</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Deaminase 3D structures|Deaminase 3D structures]]
*[[Deaminase 3D structures|Deaminase 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
[[Category: Adenine deaminase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Kumaran, D]]
[[Category: Kumaran D]]
[[Category: Structural genomic]]
[[Category: Sugadev R]]
[[Category: Sugadev, R]]
[[Category: Swaminathan S]]
[[Category: Swaminathan, S]]
[[Category: Adenine complex]]
[[Category: Amidohydrolase]]
[[Category: Binuclear zinc]]
[[Category: Hydrolase]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tim barrel]]

Latest revision as of 13:26, 12 January 2022

Crystal structure of an adenine deaminaseCrystal structure of an adenine deaminase

Structural highlights

Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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