WD repeat-containing protein: Difference between revisions

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*'''WD repeat-containing protein 48 and 20''' act as regulators of deubiquinating complexes.
*'''WD repeat-containing protein 48 and 20''' act as regulators of deubiquinating complexes.


*'''WD repeat-containing protein 41''' is the non-catalytic component of C9orf72-SMCR8 complex which regulates autophagy<ref>PMID:27193190</ref>.  <br />
*'''WD repeat-containing protein 55''' is a modulator of rRNA synthesis.  <br />
*'''WD repeat-containing protein 61''' is a component of PAF1 complex which functions during RNA transcription.  <br />
*'''WD repeat-containing protein 91''' functions as negative regulator of the PI3 kinase/PI3K activity in endosomal transport<ref>PMID:27126989</ref>.  <br />
*'''WD repeat-containing protein 92''' is a modulator of apoptosis.  <br />
*'''WD repeat-containing protein SLP1''' is required for mad2-dependent spindle checkpoint activation.  <br />
*'''WD repeat protein CSA''' or '''DNA excision repair protein ERCC-8''' is part of the transcription-coupled repair complex<ref>PMID:32355176</ref>.  <br />
== Disease ==
== Disease ==
Mutant WDR is involved in triple-A syndrome<ref>PMID:11062474</ref>.
Mutant WDR is involved in triple-A syndrome<ref>PMID:11062474</ref>.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Alexander Berchansky, Joel L. Sussman