WD repeat-containing protein: Difference between revisions
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*'''WD repeat-containing protein 48 and 20''' act as regulators of deubiquinating complexes. | *'''WD repeat-containing protein 48 and 20''' act as regulators of deubiquinating complexes. | ||
*'''WD repeat-containing protein 41''' is the non-catalytic component of C9orf72-SMCR8 complex which regulates autophagy<ref>PMID:27193190</ref>. <br /> | |||
*'''WD repeat-containing protein 55''' is a modulator of rRNA synthesis. <br /> | |||
*'''WD repeat-containing protein 61''' is a component of PAF1 complex which functions during RNA transcription. <br /> | |||
*'''WD repeat-containing protein 91''' functions as negative regulator of the PI3 kinase/PI3K activity in endosomal transport<ref>PMID:27126989</ref>. <br /> | |||
*'''WD repeat-containing protein 92''' is a modulator of apoptosis. <br /> | |||
*'''WD repeat-containing protein SLP1''' is required for mad2-dependent spindle checkpoint activation. <br /> | |||
*'''WD repeat protein CSA''' or '''DNA excision repair protein ERCC-8''' is part of the transcription-coupled repair complex<ref>PMID:32355176</ref>. <br /> | |||
== Disease == | == Disease == | ||
Mutant WDR is involved in triple-A syndrome<ref>PMID:11062474</ref>. | Mutant WDR is involved in triple-A syndrome<ref>PMID:11062474</ref>. |