5cht: Difference between revisions

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<StructureSection load='5cht' size='340' side='right'caption='[[5cht]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5cht' size='340' side='right'caption='[[5cht]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5cht]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHT FirstGlance]. <br>
<table><tr><td colspan='2'>[[5cht]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CHT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Usp18, Ubp43 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cht OCA], [http://pdbe.org/5cht PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cht RCSB], [http://www.ebi.ac.uk/pdbsum/5cht PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cht ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cht OCA], [https://pdbe.org/5cht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cht RCSB], [https://www.ebi.ac.uk/pdbsum/5cht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cht ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UBP18_MOUSE UBP18_MOUSE]] Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms (By similarity).  
[https://www.uniprot.org/uniprot/UBP18_MOUSE UBP18_MOUSE] Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Basters, A]]
[[Category: Basters A]]
[[Category: Fritz, G]]
[[Category: Fritz G]]
[[Category: Hydrolase]]
[[Category: Interferon]]
[[Category: Isg15]]
[[Category: Ubiquitin-specific protease]]

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